BPC-157 Peptide – 5mg / 10mg
BPC-157 Peptide – 5mg / 10mg
Price range: $29.99 through $175.00
5 mg or 10mg per vial
- This product is prepared for PRESCRIBER USE ONLY and may not be used for other purposes.
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Properties
| Molecular Formula | C62H98N16O22 |
|---|---|
| Molecular Weight | 1419.5 |
| Monoisotopic Mass | 1417.70415882 |
| Polar Area | 574 |
| Complexity | 3040 |
| XLogP | -9 |
| Heavy Atom Count | 100 |
| Hydrogen Bond Donor Count | 16 |
| Hydrogen Bond Acceptor Count | 24 |
| Rotatable Bond Count | 39 |
| Physical Appearance | Fine White Lyophilized Powder |
| Stability | Lyophilized protein is to be stored at -20°C. It is recommended to aliquot the reconstituted (dissolved) protein into several discrete vials in order to avoid repeated freezing and thawing. Reconstituted protein can be stored at 4°C |
| PubChem LCSS |
Identifiers
| CID | 9941957 |
|---|---|
| CAS | 137525-51-0 |
| InChI | InChI=1S/C62H98N16O22/c1-31(2)25-37(55(92)74-50(32(3)4)62(99)100)71-46(81)29-65-51(88)33(5)67-53(90)38(26-48(84)85)73-54(91)39(27-49(86)87)72-52(89)34(6)68-57(94)41-15-10-21-75(41)58(95)35(13-7-8-20-63)70-45(80)30-66-56(93)40-14-9-22-76(40)60(97)43-17-12-24-78(43)61(98)42-16-11-23-77(42)59(96)36(18-19-47(82)83)69-44(79)28-64/h31-43, 50H, 7-30, 63-64H2, 1-6H3, (H, 65, 88)(H, 66, 93)(H, 67, 90)(H, 68, 94)(H, 69, 79)(H, 70, 80)(H, 71, 81)(H, 72, 89)(H, 73, 91)(H, 74, 92)(H, 82, 83)(H, 84, 85)(H, 86, 87)(H, 99, 100)/t33-, 34-, 35-, 36-, 37-, 38-, 39-, 40-, 41-, 42-, 43-, 50-/m0/s1 |
| InChIKey | HEEWEZGQMLZMFE-RKGINYAYSA-N |
| Isomeric SMILES | C[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)O)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@@H]3CCCN3C(=O)[C@@H]4CCCN4C(=O)[C@H](CCC(=O)O)NC(=O)CN |
| Canonical SMILES | CC(C)CC(C(=O)NC(C(C)C)C(=O)O)NC(=O)CNC(=O)C(C)NC(=O)C(CC(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(C)NC(=O)C1CCCN1C(=O)C(CCCCN)NC(=O)CNC(=O)C2CCCN2C(=O)C3CCCN3C(=O)C4CCCN4C(=O)C(CCC(=O)O)NC(=O)CN |
| IUPAC Name | (4S)-4-[(2-aminoacetyl)amino]-5-[(2S)-2-[(2S)-2-[(2S)-2-[[2-[[(2S)-6-amino-1-[(2S)-2-[[(2S)-1-[[(2S)-3-carboxy-1-[[(2S)-3-carboxy-1-[[(2S)-1-[[2-[[(2S)-1-[[(1S)-1-carboxy-2-methylpropyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-2-oxoethyl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-5-oxopentanoic acid |
Description
BPC-157 Peptide: Advancing Research in Healing and Recovery
Product is sold for prescriber purposes only. Please handle with care and follow all safety guidelines for the specific chemicals involved.
What is BPC-157?
BPC-157, also known as Body Protection Compound-157, is a synthetic peptide composed of 15 amino acids. It is derived from a protein found in the stomach and has been studied for its potential therapeutic effects on various tissues, including muscles, tendons, ligaments, and the gastrointestinal tract. This white paper aims to provide a comprehensive overview of BPC-157, including its mechanisms of action, therapeutic applications, safety profile, and potential future research directions.
What are BPC-157’s main benefits?
More research is needed to determine the potential benefits of BPC-157 in humans. However, studies conducted on rodents and in vitro (cultured cells) suggest that BPC-157 may promote healing in various tissues, including tendons, joints, nerves, the intestinal tract, the stomach, and skin.
Mechanisms of Action
BPC-157 exerts its effects through multiple mechanisms, making it a versatile therapeutic agent. Key mechanisms include:
- Angiogenesis and Vasculogenesis: BPC-157 promotes the formation of new blood vessels, enhancing blood flow to damaged tissues and facilitating healing processes.
- Anti-Inflammatory Effects: It reduces inflammation by modulating the release of pro-inflammatory cytokines and increasing the production of anti-inflammatory mediators.
- Cell Proliferation and Migration: BPC-157 stimulates the proliferation and migration of various cell types, including fibroblasts and endothelial cells, which are crucial for tissue repair.
- Neuroprotective Effects: It has been shown to protect nerve cells from damage and promote nerve regeneration.
- Gastroprotective Effects: BPC-157 has a protective effect on the gastrointestinal tract, enhancing the integrity of the mucosal barrier and promoting the healing of ulcers.
Future Research Directions
Despite promising results, further research is necessary to fully understand the therapeutic potential of BPC-157. Future research should focus on:
- Clinical Trials: Conducting large-scale, randomized controlled trials to confirm the efficacy and safety of BPC-157 in various conditions.
- Mechanistic Studies: Elucidating the precise molecular mechanisms by which BPC-157 exerts its effects.
- Long-term Safety: Assessing the long-term safety of BPC-157, especially with prolonged use.
- Combination Therapies: Exploring the potential synergistic effects of BPC-157 with other therapeutic agents.
Conclusion
BPC-157 is a promising therapeutic peptide with a broad range of potential applications, particularly in tissue repair and inflammation management. Its safety profile and multifaceted mechanisms of action make it a candidate for further clinical development. Continued research and clinical trials will be essential to fully realize the therapeutic potential of BPC-157 and integrate it into mainstream medical practice.
Synonyms:
BPC 157; BPC-157; Body protection compound 15;
Peer-Reviewed Sources:
- “Gastric pentadecapeptide BPC 157 as an original anti-ulcer agent and organoprotection peptide” – This study discusses BPC-157’s potential in protecting organs and healing ulcers. PubMed PMID: 8964320
- “Stable gastric pentadecapeptide BPC 157 as a prototype stable mediator, counteracting adrenergic activation and arrhythmias” – Investigates BPC-157’s effects on adrenergic activation and arrhythmias. PubMed PMID: 17131965
- “The effect of gastric pentadecapeptide BPC 157 on NSAID-induced damage” – Explores how BPC-157 mitigates damage caused by non-steroidal anti-inflammatory drugs. PubMed PMID: 10322125
- “Gastric pentadecapeptide BPC 157 in healing of segmental bone defect in rabbits” – Evaluates BPC-157’s efficacy in bone healing. PubMed PMID: 11124436
- “Gastric pentadecapeptide BPC 157 promotes the healing of transected rat Achilles tendon” – Investigates BPC-157’s role in tendon healing. PubMed PMID: 9575887
- “Gastric pentadecapeptide BPC 157 and the healing of transected quadriceps muscle in rats” – Focuses on muscle healing properties of BPC-157. PubMed PMID: 9855553
- “Stable gastric pentadecapeptide BPC 157: novel therapy in gastrointestinal tract” – Reviews BPC-157 as a therapeutic agent for gastrointestinal issues. PubMed PMID: 10875537
- “Gastric pentadecapeptide BPC 157 effective therapy for chronic alcohol-induced gastric lesions in rats” – Studies the effect of BPC-157 on alcohol-induced gastric lesions. PubMed PMID: 8597897
ALL LITERATURE, INFORMATION, AND DATA, PROVIDED ON THIS WEBSITE ARE FOR INFORMATIONAL AND EDUCATIONAL PURPOSES ONLY.
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