Thymalin – 10mg
Properties
| Molecular Formula | |
|---|---|
| Molecular Weight | 858.860 g/mol |
| Monoisotopic Mass | |
| Polar Area | 858.9 g/mol |
| Complexity | |
| XLogP | |
| Heavy Atom Count | |
| Hydrogen Bond Donor Count | |
| Hydrogen Bond Acceptor Count | |
| Rotatable Bond Count | |
| Physical Appearance | Fine White Lyophilized Powder |
| Stability | |
| PubChem LCSS |
Identifiers
| CID | |
|---|---|
| CAS | 63958-90-7 |
| InChI | InChI=1S/C33H54N12O15/c1-15(39-29(55)18-6-8-24(50)40-18)27(53)42-16(4-2-3-9-34)30(56)45-21(14-47)32(58)43-17(5-7-22(35)48)28(54)38-11-25(51)37-12-26(52)41-20(13-46)31(57)44-19(33(59)60)10-23(36)49/h15-21,46-47H,2-14,34H2,1H3,(H2,35,48)(H2,36,49)(H,37,51)(H,38,54)(H,39,55)(H,40,50)(H,41,52)(H,42,53)(H,43,58)(H,44,57)(H,45,56)(H,59,60)/t15-,16-,17-,18-,19-,20-,21-/m0/s1 |
| InChIKey | LIFNDDBLJFPEAN-BPSSIEEOSA-N |
| Isomeric SMILES | NCCCC[C@H](NC([C@H](C)NC([C@@H]1CCC(N1)=O)=O)=O)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(NCC(NCC(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(O)=O)=O)=O)=O)=O)=O)=O |
| Canonical SMILES | |
| IUPAC Name | ((S)-5-oxopyrrolidine-2-carbonyl)-L-alanyl-L-lysyl-L-seryl-L-glutaminylglycylglycyl-L-seryl-L-asparagine |
Description
Thymalin
Product is sold for prescriber purposes only. Please handle with care and follow all safety guidelines for the specific chemicals involved.
Thymalin, a synthetic thymic peptide, has shown promising applications in rat research for understanding its effects on immune modulation, anti-inflammatory action, and regenerative processes. Studies have highlighted its ability to restore thymic function and enhance cellular immunity, making it particularly relevant for conditions involving immune suppression or chronic inflammation.
For instance, research on rats with thyroidectomy demonstrated that Thymalin reversed immune and cellular growth impairments, restoring thymic activity and supporting overall health. This has been associated with increased lymphocyte proliferation and improved immune response (Khavinson et al., 2020). Another study highlighted its potential in reducing tumor progression in rat models, with findings showing tumor regression in over 50% of cases and halted growth in nearly 80% of instances when administered at therapeutic concentrations.
Additionally, Thymalin’s impact on systemic inflammation has been studied in conditions such as diabetic retinopathy and psoriasis, where it demonstrated reductions in disease severity by modulating immune and inflammatory markers. This underscores its potential as an adjunct therapy in chronic immune-inflammatory diseases (Morozov et al., 1997).
Overall, Thymalin serves as a valuable tool in preclinical research, with implications spanning immunology, oncology, and regenerative medicine. However, further studies are warranted to fully elucidate its mechanisms and therapeutic potential in clinical settings.
References:
- Khavinson VK, et al. Bulletin of Experimental Biology and Medicine, 2020. PMID: 33237528
- Morozov VG, et al. International Journal of Immunopharmacology, 1997. DOI:10.1016/s0192-0561(97)00058-1
- Khavinson VK, et al. Advances in Gerontology, 2002. PMID: 12577695
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